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Neurovascular coupling and CO2 interrogate distinct vascular regulations

Abstract Neurovascular coupling (NVC), which mediates rapid increases in cerebral blood flow in response to neuronal activation, is commonly used to map brain activation or dysfunction. Here we tested the reemerging hypothesis that CO2 generated by neuronal metabolism contributes to NVC. We combined...

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Main Authors: Marine Tournissac, Emmanuelle Chaigneau, Sonia Pfister, Ali-Kemal Aydin, Yannick Goulam Houssen, Philip O’Herron, Jessica Filosa, Mayeul Collot, Anne Joutel, Serge Charpak
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49698-9
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