Dosimetric analysis reveals rapid clearance and low absorbed dose of [¹⁷⁷Lu]Lu-PSMA-617 in non-prostate cancers with high PSMA expression

Abstract Background The aim of this study was to evaluate the dosimetry for [177Lu]Lu-PSMA-617 in advanced non-prostate cancer (non-PCa) patients with previous intense radiotracer uptake of the tumor lesions on PET/CT using [68Ga]Ga-PSMA-11. Results Dosimetry data of 5 patients with non-prostate can...

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Detalhes bibliográficos

Principais autores:	Fadi Khreish, Florian Rosar, Caroline Burgard, Sven Petto, Stephan Maus, Tobias Stemler, Mark Bartholomä, Amir Sabet, Andrea Schaefer-Schuler, Samer Ezziddin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2026-02-01
Colecção:	EJNMMI Research
Assuntos:	Dosimetry [177Lu]Lu-PSMA-617 Radioligand therapy RLT Non-prostate malignancy
Acesso em linha:	https://doi.org/10.1186/s13550-026-01394-z
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