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Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis

Abstract Background Viridans group streptococci of the Streptococcus mitis-oralis subgroup are important endovascular pathogens. They can rapidly develop high-level and durable non-susceptibility to daptomycin both in vitro and in vivo upon exposure to daptomycin. Two consistent genetic adaptations...

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Principais autores: Allison Parrett, Joseph M. Reed, Stewart G. Gardner, Nagendra N. Mishra, Arnold S. Bayer, Robert Powers, Greg A. Somerville
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-06-01
Serier:BMC Microbiology
Fag:
Streptococcus
Metabolism
Antibiotic resistance
Daptomycin
Online adgang:http://link.springer.com/article/10.1186/s12866-020-01849-w
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