Proteomic profiling revealed unique disease biology associated with 1q abnormalities in multiple myeloma

Abstract Gain or amplification of chromosome 1q (+1q) is a common genomic alteration occurring in the plasma cells in nearly 40% of multiple myeloma patients. Although it is associated with inferior outcomes and is more common in the relapsed or refractory stages, the impact of +1q at the proteomic...

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Principais autores:	Kiran K. Mangalaparthi, Joel-Sean Hsu, J. Erin Wiedmeier-Nutor, Partho Sen, Julie Staub, Firdous A. Bhat, Caleb K. Stein, Greg J. Ahmann, Shaji K. Kumar, S. Vincent Rajkumar, P. Leif Bergsagel, Rafael Fonseca, Esteban Braggio, Richard K. Kandasamy, Akhilesh Pandey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-04-01
coleção:	npj Precision Oncology
Acesso em linha:	https://doi.org/10.1038/s41698-026-01364-7
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