Exploring the role of stromal osmoregulation in cancer and disease using executable modelling

Aberrant ion transporter expression disrupts osmoregulation in many cancers. Here, the authors introduce an executable model of osmotic regulation and membrane transport, illuminating the mechanistic basis of multiple cellular cancer phenotypes and suggesting therapeutic avenues.

Podrobná bibliografie

Hlavní autoři:	David Shorthouse, Angela Riedel, Emma Kerr, Luisa Pedro, Dóra Bihary, Shamith Samarajiwa, Carla P. Martins, Jacqueline Shields, Benjamin A. Hall
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2018-08-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-018-05414-y
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