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Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4′-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives

Abstract Background Pyrimidine molecules attracted organic chemists very much due to their biological and chemotherapeutic importance. Their related fused heterocycles are of interest as potential bioactive molecules so, we have designed and prepared a new class of 4,4′-(1,4-phenylene)bis(pyrimidin-...

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Hlavní autoři: Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah, Balasubramanian Narasimhan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-06-01
Edice:Chemistry Central Journal
Témata:
Pyrimidine molecules
Design
Synthesis
Antimicrobial
Cytotoxicity
HCT116
On-line přístup:http://link.springer.com/article/10.1186/s13065-018-0440-3
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