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A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.

Parasites of the phylum Apicomplexa cause diseases that impact global health and economy. These unicellular eukaryotes possess a relict plastid, the apicoplast, which is an essential organelle and a validated drug target. However, much of its biology remains poorly understood, in particular its elab...

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主要な著者: Lilach Sheiner, Jessica L Demerly, Nicole Poulsen, Wandy L Beatty, Olivier Lucas, Michael S Behnke, Michael W White, Boris Striepen
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2011-12-01
シリーズ:PLoS Pathogens
オンライン・アクセス:http://europepmc.org/articles/PMC3228799?pdf=render
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