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TLR1 Variant H305L Associated with Protection from Pulmonary Tuberculosis.

Toll like receptors (TLR) are key elements of the innate immune response and involved in the recognition of pathogens. To test common and rare TLR variants involved in susceptibility or resistance to infection with Mycobacterium tuberculosis we screened the exons of the genes encoding TLR 1, 2, 4, a...

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Autors principals: Christian G Meyer, Norbert Reiling, Christa Ehmen, Gerd Ruge, Ellis Owusu-Dabo, Rolf D Horstmann, Thorsten Thye
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2016-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0156046
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