Genetically predicted gut bacteria, circulating bacteria-associated metabolites and pancreatic ductal adenocarcinoma: a Mendelian randomisation study

Abstract Pancreatic ductal adenocarcinoma (PDAC) has high mortality and rising incidence rates. Recent data indicate that the gut microbiome and associated metabolites may play a role in the development of PDAC. To complement and inform observational studies, we investigated associations of genetica...

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Váldodahkkit:	Neil Daniel, Riccardo Farinella, Anastasia Chrysovalantou Chatziioannou, Mazda Jenab, Ana-Lucia Mayén, Cosmeri Rizzato, Flavia Belluomini, Federico Canzian, Arianna Tavanti, Pekka Keski-Rahkonen, David J. Hughes, Daniele Campa
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2024-10-01
Ráidu:	Scientific Reports
Fáttát:	Mendelian randomisation Gut microbiome Bacteria-related metabolites Pancreatic ductal adenocarcinoma
Liŋkkat:	https://doi.org/10.1038/s41598-024-77431-5
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