Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation

Abstract Background The changes in DNA methylation patterns may reflect both physical and mental well-being, the latter being a relatively unexplored avenue in terms of clinical utility for psychiatric disorders. In this study, our objective was to identify the methylation-based biomarkers for anxie...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yoonsung Kwon, Asta Blazyte, Yeonsu Jeon, Yeo Jin Kim, Kyungwhan An, Sungwon Jeon, Hyojung Ryu, Dong-Hyun Shin, Jihye Ahn, Hyojin Um, Younghui Kang, Hyebin Bak, Byoung-Chul Kim, Semin Lee, Hyung-Tae Jung, Eun-Seok Shin, Jong Bhak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-02-01
coleção:	Clinical Epigenetics
Assuntos:	Anxiety disorder Methylation risk score Machine learning Epigenetic biomarker Liquid biopsy
Acesso em linha:	https://doi.org/10.1186/s13148-025-01819-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!