Mechanical cues as immunomodulators in neuroinflammation-driven spinal sensitization: analgesic mechanisms and therapeutic strategies

Neuroinflammation is a key immunological driver of spinal sensitization and the transition from acute to chronic pain. Although mechanical interventions can reduce pain, the immuno-inflammatory mechanisms linking mechanical cues to resolution of spinal neuroinflammation remain poorly integrated and...

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Autors principals:	Li-ya Tang, Ke-shang Li, Xiao-xia Kuang, Jiang-shan Li, Xiang Feng, Wu Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	analgesia immunoregulation mechanical stimulation neuroinflammation spinal sensitization
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1791900/full
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