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ZIC2 drives colorectal cancer progression by regulating QPRT-mediated cell migration

BackgroundColorectal cancer (CRC) is characterized by high mortality. Zinc finger protein ZIC2 plays a dual role in various cancers; however, its clinical value of ZIC2 in CRC remains unclear.MethodsTCGA cohort data, GEO datasets (GSE39582 and GSE139555), and a CRC_10x spatial transcriptomics datase...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Liken Zheng, Hao Liu, Ailing Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-01-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1722707/full
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