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Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium

<p>Abstract</p> <p>Background</p> <p>The production of gamma-amino butyric acid (GABA) is dependent on glutamate decarboxylases (GAD65 and GAD67), the enzymes that catalyze the decarboxylation of glutamate to GABA. Based on studies suggesting a role of the airway epithelial GABAergic system in asthm...

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Auteurs principaux: Strulovici-Barel Yael, Salit Jacqueline, Ferris Barbara, Wang Rui, Wang Guoqing, Hackett Neil R, Crystal Ronald G
Format: Artigo
Langue:Inglês
Publié: BMC 2010-10-01
Collection:Respiratory Research
Accès en ligne:http://respiratory-research.com/content/11/1/150
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