Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule ¹⁸⁸Re-ZHER2:41071

HER2-targeted radionuclide therapy might be helpful for the treatment of breast, gastric, and ovarian cancers which have developed resistance to antibody and antibody-drug conjugate-based therapies despite preserved high HER2-expression. Affibody molecules are small targeting proteins based on a non...

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Autori principali:	Yongsheng Liu, Anzhelika Vorobyeva, Anna Orlova, Mark W. Konijnenberg, Tianqi Xu, Olga Bragina, Annika Loftenius, Erica Rosander, Fredrik Y. Frejd, Vladimir Tolmachev
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-05-01
Serie:	Pharmaceutics
Soggetti:	HER2 radionuclide therapy affibody molecule rhenium-188 second-generation scaffold
Accesso online:	https://www.mdpi.com/1999-4923/14/5/1092
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