Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines

The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of 4-carboranyl-3-nitro-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, were synthesised via amidation and reductive amination reaction...

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Bibliografski detalji

Glavni autori:	Sebastian Rykowski, Dorota Gurda-Woźna, Agnieszka Fedoruk-Wyszomirska, Marta Orlicka-Płocka, Aleksandra Kowalczyk, Paweł Stączek, Marta Denel-Bobrowska, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Eliza Wyszko, Agnieszka B. Olejniczak
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis Group 2023-12-01
Serija:	Journal of Enzyme Inhibition and Medicinal Chemistry
Teme:	Carborane 1,8-naphthalimides intercalation anticancer activity
Online pristup:	https://www.tandfonline.com/doi/10.1080/14756366.2023.2171028
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