The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.

<h4>Background</h4>Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide polymorphism (SNP) on disease sus...

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Detalhes bibliográficos

Principais autores:	Martin Storr, Dominik Emmerdinger, Julia Diegelmann, Simone Pfennig, Thomas Ochsenkühn, Burkhard Göke, Peter Lohse, Stephan Brand
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2010-02-01
coleção:	PLoS ONE
Acesso em linha:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195480/pdf/?tool=EBI
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