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Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy

Allergen-specific immunotherapy (AIT) is the only currently available curative treatment option for allergic diseases. AIT often includes depot-forming and immunostimulatory adjuvants, to prolong allergen presentation and to improve therapeutic efficacy. The use of aluminium salts in AIT, which are...

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Autori principali: Sonja Heine, Antonio Aguilar-Pimentel, Dennis Russkamp, Francesca Alessandrini, Valerie Gailus-Durner, Helmut Fuchs, Markus Ollert, Reinhard Bredehorst, Caspar Ohnmacht, Ulrich M. Zissler, Martin Hrabě de Angelis, Carsten B. Schmidt-Weber, Simon Blank
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-07-01
Serie:Pharmaceutics
Soggetti:
allergen-specific immunotherapy
allergic asthma
antigen release
hydrogel
delivery system
depot matrix
Accesso online:https://www.mdpi.com/1999-4923/14/8/1527
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