VOLTAGE-GATED SODIUM CHANNELS AND CANCER: IS EXCITABILITY THEIR PRIMARY ROLE?

Voltage-gated sodium channels (NaV) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by A. Hodgkin and A. Huxley u...

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Bibliografiske detaljer

Principais autores:	Sébastien eRoger, Ludovic eGillet, Jean-Yves eLe Guennec, Pierre eBesson
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2015-07-01
Serier:	Frontiers in Pharmacology
Fag:	Sodium Cancer invasion voltage-gated sodium channels Cell excitability
Online adgang:	http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00152/full
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