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Polysorbates degrading enzymes in biotherapeutics – a current status and future perspectives

Polysorbates, in particular polysorbate (PS) 20 and 80, are the most commonly used surfactants for stabilising biotherapeutics produced by biotechnological processes. PSs are derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids of varying chain length and degree o...

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Autors principals: Marius Nicolaus Felix, Thomas Waerner, Daniel Lakatos, Bernd Reisinger, Simon Fischer, Patrick Garidel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2025-01-01
Col·lecció:Frontiers in Bioengineering and Biotechnology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1490276/full
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