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Whole transcriptome analysis of peripheral blood identifies systemic innate immune responses and translation inhibition in subclinical Holstein cattle naturally infected with Mycobacterium avium subsp. paratuberculosis

Bovine paratuberculosis (PTB), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic granulomatous intestinal disease that leads to substantial economic losses in the global dairy industry. Current diagnostic tests have limited sensitivity, as they can reliably detect only animal...

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Principais autores: Arrate Prado-López, Gerard Badia-Bringué, Rosana Torremocha, Alejandra I. Navarro León, Rosa Casais, Marta Alonso-Hearn
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-05-01
Serier:Frontiers in Immunology
Fag:
biomarkers
innate immune response
paratuberculosis
RNA-Seq
translation inhibition
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1744978/full
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