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OGA promotes human dental pulp stem cell senescence and inhibits mitophagy by inhibition of O-GlcNAcylation of KLF2

Abstract Background Dental pulp stem cells (DPSCs) aging impedes its application in tooth regeneration techniques, involving abnormal mitophagy. O-GlcNAcylation is a post-translational modification that regulates various cellular processes. Here, we aimed to investigate the role of O-GlcNAcylation i...

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Autori principali: Yinhao Ding, Yan Ran
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-04-01
Serie:BMC Oral Health
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Accesso online:https://doi.org/10.1186/s12903-025-05927-1
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