Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

Abstract Background Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2). This study aims to explore how butyrate alleviates liver fibrosis in BA thr...

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Detalhes bibliográficos

Principais autores:	Yilin Zhao, Xiaodan Xu, Shaowen Liu, Xueting Wang, Jiayinaxi Musha, Tengfei Li, Liang Ge, Yan Sun, Shujian Zhang, Li Zhao, Jianghua Zhan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
coleção:	BMC Pediatrics
Assuntos:	Biliary atresia Fibrosis Butyrate HDAC2 IL-6 STAT3
Acesso em linha:	https://doi.org/10.1186/s12887-025-05635-3
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