Whole-Exome Sequencing in Family Trios Reveals De Novo Mutations Associated with Type 1 Diabetes Mellitus

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease characterized by insulin deficiency and loss of pancreatic islet β-cells. The objective of this study is to identify de novo mutations in 13 trios from singleton families that contribute to the genetic basis of T1DM through the applicat...

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Hlavní autoři:	Mira Mousa, Sara Albarguthi, Mohammed Albreiki, Zenab Farooq, Sameeha Sajid, Sarah El Hajj Chehadeh, Gihan Daw ElBait, Guan Tay, Asma Al Deeb, Habiba Alsafar
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-03-01
Edice:	Biology
Témata:	type 1 diabetes WES case–parent trios de novo variants family trios T1D
On-line přístup:	https://www.mdpi.com/2079-7737/12/3/413
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