Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) leads to progressive memory decline, and alterations in hippocampal function are among the earliest pathological features observed in human and animal studies. GABAergic interneurons (INs) within the hippocampus coordinate network activity, among which type 3 interneuron-spe...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Felix Michaud, Ruggiero Francavilla, Dimitry Topolnik, Parisa Iloun, Suhel Tamboli, Frederic Calon, Lisa Topolnik
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	eLife Sciences Publications Ltd 2024-09-01
Schriftenreihe:	eLife
Schlagworte:	hippocampus memory Alzheimer's disease circuit inhibition disinhibition
Online-Zugang:	https://elifesciences.org/articles/95412
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!