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Distinct genetic signals at the FGF21 locus complicate studies of FGF21's role in diet regulation using human cohort data

Objectives: Experimental and genetic studies suggest that fibroblast growth factor 21 (FGF21) modulates macronutrient and alcohol preferences, but evidence of such regulation in humans remains scarce. To address this gap in translation, we aimed to map the relationships between plasma FGF21 levels,...

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Principais autores: Stina Ramne, Mario García-Ureña, Matthew P. Gillum, Lars Ängquist, Torben Hansen, Jordi Merino, Niels Grarup
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-12-01
coleção:Molecular Metabolism
Assuntos:
Fibroblast growth factor 21
Macronutrients
Alcohol
Diet preference
Mendelian randomization
Nutrigenetics
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212877824001807
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