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Periovulatory neurohormone dynamics reveal an association between secretoneurin and GnRH across the mouse estrous cycle

IntroductionSurge release of luteinizing hormone (LH) from the pituitary is essential for fertility, as it triggers ovulation. Secretoneurin (SN), a conserved peptide derived from secretogranin-2, stimulates LH release, but its relationship to periovulatory changes in classical reproductive hormones...

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Principais autores: Chunyu Lu, Di Peng, Kevin B. Smith, Chinelo Uju, Suraj Unniappan, Paula Duarte-Guterman, Nafissa Ismail, Vance L. Trudeau
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-01-01
Serier:Frontiers in Endocrinology
Fag:
arginine vasopressin
estradiol
gonadotropin-releasing hormone
luteinizing hormone
oxytocin
progesterone
Online adgang:https://www.frontiersin.org/articles/10.3389/fendo.2025.1708570/full
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