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Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.

BACKGROUND: The forkhead transcription factors of the O class (FOXO) play a direct role in cellular proliferation, oxidative stress response, and tumorigenesis. The objectives of this study were to examine whether FOXOs regulate antitumor activities of resveratrol in pancreatic cancer cells in vitro...

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Hauptverfasser: Sanjit K Roy, Qinghe Chen, Junsheng Fu, Sharmila Shankar, Rakesh K Srivastava
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3181262?pdf=render
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