Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain

Background/Aims: Conjugated linoleic acids (CLAs) affect body fat distribution, induce insulin resistance and stimulate insulin secretion. The latter effect is mediated through the free fatty acid receptor-1 (GPR40/FFAR1). This study examines whether GPR40/FFAR1 interacts with tissue specific metabo...

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Principais autores:	Tina Sartorius, Andrea Drescher, Madhura Panse, Petr Lastovicka, Andreas Peter, Cora Weigert, Evi Kostenis, Susanne Ullrich, Hans-Ulrich Häring
Format:	Artigo
Jezik:	Inglês
Izdano:	Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Serija:	Cellular Physiology and Biochemistry
Teme:	CLA Electrocorticography Ffar1-/- mouse FFAR1 GPR40 Brain inflammation Radiotelemetry Insulin resistance Fatty liver Brain insulin resistance
Online dostop:	http://www.karger.com/Article/FullText/374031
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