A combined bioinformatics and experimental approach identifies RMI2 as a Wnt/β-catenin signaling target gene related to hepatocellular carcinoma

Abstract Background The Wnt/β-catenin signaling pathway plays an important role in embryogenesis and tumorigenesis. In human cancer, abnormal activity of Wnt/β-catenin signaling pathway induces overexpressed of downstream genes, and initiate oncogene. There are several target genes known to be key p...

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Principais autores:	Hung-Wen Tsai, Shu-Wen Cheng, Chou-Cheng Chen, I-Wen Chen, Chung-Liang Ho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
Colecção:	BMC Cancer
Assuntos:	RMI2 β-Catenin/TCF complex Wnt target genes Bioinformatics
Acesso em linha:	https://doi.org/10.1186/s12885-023-10655-2
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