SLC7A11 alleviates diquat-induced neurotoxicity by inhibiting ferroptosis and preserving mitochondrial function

Diquat (DQ), a widely used bipyridyl herbicide, poses a significant neurotoxic threat through poorly understood mechanisms. This study demonstrated that restoring SLC7A11 expression effectively mitigated DQ-induced neurotoxicity by suppressing ferroptosis and mitochondrial dysfunction. We employed i...

Full description

Bibliographic Details

Main Authors:	Yaolu Zhang, Yingying Jiang, Yan Li, Fangfang Wu, Guanqi Chen, Zhongqiu Lu
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2026-01-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Diquat Ferroptosis SLC7A11 Neurotoxicity Mitochondrial dysfunction
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651326000230
Tags:	Add Tag No Tags, Be the first to tag this record!