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SLC7A11 alleviates diquat-induced neurotoxicity by inhibiting ferroptosis and preserving mitochondrial function

Diquat (DQ), a widely used bipyridyl herbicide, poses a significant neurotoxic threat through poorly understood mechanisms. This study demonstrated that restoring SLC7A11 expression effectively mitigated DQ-induced neurotoxicity by suppressing ferroptosis and mitochondrial dysfunction. We employed i...

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Principais autores: Yaolu Zhang, Yingying Jiang, Yan Li, Fangfang Wu, Guanqi Chen, Zhongqiu Lu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-01-01
Serier:Ecotoxicology and Environmental Safety
Fag:
Diquat
Ferroptosis
SLC7A11
Neurotoxicity
Mitochondrial dysfunction
Online adgang:http://www.sciencedirect.com/science/article/pii/S0147651326000230
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