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Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.

Persistence of a reservoir of latently infected memory T cells provides a barrier to HIV eradication in treated patients. Several reports have implicated the involvement of SWI/SNF chromatin remodeling complexes in restricting early steps in HIV infection, in coupling the processes of integration an...

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Bibliografiske detaljer
Principais autores: Haleh Rafati, Maribel Parra, Shweta Hakre, Yuri Moshkin, Eric Verdin, Tokameh Mahmoudi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2011-11-01
Serier:PLoS Biology
Online adgang:http://europepmc.org/articles/PMC3226458?pdf=render
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