The D826V point mutation in IREB2 induces lipogenesis in adipose tissues
BackgroundIREB2 is an RNA-binding protein that modulates cellular iron uptake and storage by regulating ferritin expression. Mutations in the IREB2 gene have been shown to induce degradation of the IREB2 protein, resulting in the upregulation of FTH1 protein expression, which contributes to iron sto...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2026-01-01
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| Schriftenreihe: | Frontiers in Cell and Developmental Biology |
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| Online-Zugang: | https://www.frontiersin.org/articles/10.3389/fcell.2026.1724485/full |
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