Optimizing the in vitro production of immunomodulatory cells for the induction of tolerance in solid organ transplantation.

<h4>Background</h4>Cell therapy can be utilized to induce operational tolerance following solid organ transplantation. In thi study, donor-specific immunomodulatory cells (DSIMC) are generated by co-culturing recipient peripheral blood mononuclear cells (PBMC) with irradiated donor PBMC...

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Main Authors: Nils Ågren, Ming Yao, Carl Skantze, Keyvan Habibi, Bo-Göran Ericzon, Makiko Kumagai-Braesch
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0333356
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