Encapsulation and Delivery of Mitoxantrone Using Zirconium-Based Metal–Organic Frameworks (MOFs) and Their Cytotoxic Potential in Breast Cancer Cells

Mitoxantrone (MTX) is a drug employed in breast cancer treatment, but its application is largely limited due to side effects. A controlled delivery approach can potentially reduce the side effects. In this study, two zirconium (Zr)-based MOFs, UiO-66 and UiO-66-NH₂, were studied for a mor...

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Hlavní autoři:	Mitali Singhal, Kirsten Riches-Suman, Klaus Pors, Matthew A. Addicoat, Amalia Ruiz, Sanjit Nayak, Jacobo Elies
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-02-01
Edice:	Applied Sciences
Témata:	metal–organic frameworks breast cancer UiO-66 UiO-66-NH<sub>2</sub> Mitoxantrone
On-line přístup:	https://www.mdpi.com/2076-3417/14/5/1902
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