Hydralazine represses Fpn ubiquitination to rescue injured neurons via competitive binding to UBA52

A major impedance to neuronal regeneration after peripheral nerve injury (PNI) is the activation of various programmed cell death mechanisms in the dorsal root ganglion. Ferroptosis is a form of programmed cell death distinguished by imbalance in iron and thiol metabolism, leading to lethal lipid pe...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Shengyou Li, Xue Gao, Yi Zheng, Yujie Yang, Jianbo Gao, Dan Geng, Lingli Guo, Teng Ma, Yiming Hao, Bin Wei, Liangliang Huang, Yitao Wei, Bing Xia, Zhuojing Luo, Jinghui Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Journal of Pharmaceutical Analysis
Assuntos:	Ferroptosis UBA52 Ferroportin Ubiquitination Hydralazine Peripheral nerve injury
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S209517792300196X
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!