TGF-β Induces Up-Regulation of Chondroitin Sulfate Synthase 1 (CHSY1) in Nucleus Pulposus Cells Through MAPK Signaling

Background/Aims: Chondroitin sulfate synthase 1 (CHSY1) is a glycosyltransferases involved in the biosynthesis of chondroitin and dermatan sulfate glycosaminoglycan (GAG). TGF-β can stimulate sulfated GAG production in nucleus pulposus cells; however, the underlying mechanisms are poorly understood....

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Hlavní autoři:	Bo Hu, Changgui Shi, Ye Tian, Ying Zhang, Chen Xu, Huajiang Chen, Peng Cao, Wen Yuan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Edice:	Cellular Physiology and Biochemistry
Témata:	Nucleus pulposus CHSY1 TGF-β MAPK
On-line přístup:	http://www.karger.com/Article/FullText/430396
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