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Pathophysiological Roles of Mucosal-Associated Invariant T Cells in the Context of Gut Microbiota-Liver Axis

Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes expressing a semi-invariant T-cell receptor (TCR) present as TCR <i>V</i>α7.2-<i>J</i>α33 in humans and TCR <i>V</i>α19-<i>J</i>α33 in mice. They are activated by ligands produced during microbial biosynthesis of riboflavin th...

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Autori principali: Yoseph Asmelash Gebru, Mi Ran Choi, Ganesan Raja, Haripriya Gupta, Satya Priya Sharma, Ye Rin Choi, Hyeong Seop Kim, Sang Jun Yoon, Dong Joon Kim, Ki Tae Suk
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-02-01
Serie:Microorganisms
Soggetti:
MAIT cell
MR1
gut-microbiota
riboflavin metabolites
liver disease
Accesso online:https://www.mdpi.com/2076-2607/9/2/296
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