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New Human Follitropin Preparations: How Glycan Structural Differences May Affect Biochemical and Biological Function and Clinical Effect

It is well accepted that pituitary follitropin is secreted into the circulation as a mixture of variants, which differ not in primary structure but rather at the level of glycosylation. These glycosidic forms vary in the number of glycosylation sites filled, complexity of glycosidic chains, and sial...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: James A. Dias, Alfredo Ulloa-Aguirre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-03-01
Schriftenreihe:Frontiers in Endocrinology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fendo.2021.636038/full
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