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Impact of Early Versus Late Antiretroviral Treatment Initiation on Naive T Lymphocytes in HIV-1-Infected Children and Adolescents – The-ANRS-EP59-CLEAC Study

BackgroundThe early initiation of antiretroviral therapy (ART) in HIV-1-infected infants reduces mortality and prevents early CD4 T-cell loss. However, the impact of early ART on the immune system has not been thoroughly investigated in children over five years of age or adolescents. Here, we descri...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Pierre Frange, Thomas Montange, Jérôme Le Chenadec, Damien Batalie, Ingrid Fert, Catherine Dollfus, Albert Faye, Stéphane Blanche, Anne Chacé, Corine Fourcade, Isabelle Hau, Martine Levine, Nizar Mahlaoui, Valérie Marcou, Marie-Dominique Tabone, Florence Veber, Alexandre Hoctin, Thierry Wack, Véronique Avettand-Fenoël, Josiane Warszawski, Florence Buseyne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-04-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
HIV-1
children
adolescents
early ART
T lymphocyte
naive T lymphocyte
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.662894/full
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