Set-Up and Validation of a High Throughput Screening Method for Human Monoacylglycerol Lipase (MAGL) Based on a New Red Fluorescent Probe

Monoacylglycerol lipase (MAGL) is a serine hydrolase that has a key regulatory role in controlling the levels of 2-arachidonoylglycerol (2-AG), the main signaling molecule in the endocannabinoid system. Identification of selective modulators of MAGL enables both to provide new tools for investigatin...

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Autori principali:	Matteo Miceli, Silvana Casati, Roberta Ottria, Simone Di Leo, Ivano Eberini, Luca Palazzolo, Chiara Parravicini, Pierangela Ciuffreda
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2019-06-01
Serie:	Molecules
Soggetti:	high-throughput screening endocannabinoid monoacylglycerol lipase assay development
Accesso online:	https://www.mdpi.com/1420-3049/24/12/2241
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