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Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m6A modification of lncRNA MEG3

BackgroundOur previous studies have demonstrated that Xinfeng Capsule (XFC) exerts therapeutic effects on hyperinflammation-associated hypercoagulability and self-perception of patients (SPP) with osteoarthritis (OA). However, the underlying molecular mechanisms remain unclear.ObjectiveThis study ai...

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Main Authors: Mingyu He, Jian Liu, Yanqiu Sun, Yanyan Fang, Fanfan Wang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-01-01
Series:Frontiers in Immunology
Subjects:
hyperinflammation- associated hypercoagulability
lncRNA MEG3
METTL14
osteoarthritis
Xinfeng capsule
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1749727/full
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