A blood transcriptomic signature anchored to central nervous system pathology enables noninvasive detection of multiple sclerosis

Background: Multiple sclerosis (MS) lacks noninvasive biomarkers anchored to central nervous system (CNS) pathology. This study aimed to identify a blood transcriptional signature anchored to CNS lesion biology for noninvasive MS detection. Methods: We analyzed bulk RNA-seq data from MS white matter...

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Prif Awduron:	Zhen Zhu, Li-Ping Huang, Hao-Jie Yin Jin, Hai-Qian Zhou, Jia-Wei Zhang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2026-09-01
Cyfres:	Neurobiology of Disease
Pynciau:	Multiple sclerosis Blood transcriptional signature White matter lesions Microglia Machine learning
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0969996126002457
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!