Quantitative analysis of drug–drug interactions among active components of Xuebijing in inhibiting LPS-induced TLR4 signaling and NO production

Abstract Despite the long history of Traditional Chinese Medicine (TCM) in disease treatment, the underlying “Jun–Chen–Zuo–Shi” principle remains largely unexplored. To address this gap, it is essential to elucidate the interactions between active substances in TCM through quantitative molecular and...

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Detalhes bibliográficos

Principais autores:	Tianshu Zhang, Hongyuan Li, Cong Lin, Xiaohui Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-04-01
coleção:	Scientific Reports
Assuntos:	Xuebijing Traditional Chinese medicine Toll-like receptor 4 Chou–Talalay method Drug combination Nitric oxide
Acesso em linha:	https://doi.org/10.1038/s41598-025-95994-9
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