Glutamine deamidation does not increase the immunogenicity of C-peptide in people with type 1 diabetes
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease in which the insulin-producing beta cells are destroyed. While it is clear that full-length C-peptide, derived from proinsulin, is a major antigen in human T1D it is not clear how and why C-peptide becomes a target of the autoimmune CD4+...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2023-01-01
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| Col·lecció: | Journal of Translational Autoimmunity |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2589909022000417 |
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