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Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation

In the present study, 5-arylidene rhodanine derivatives 3a–f, N-glucosylation rhodanine 6, S-glucosylation rhodanine 7, N-glucoside rhodanine 8 and S-glucosylation 5-arylidene rhodanines 13a–c were synthesised and screened for cytotoxicity against a panel of cancer cells with investigating the effec...

Повний опис

Збережено в:
Бібліографічні деталі
Автори: Ahmed I. Khodair, Fatimah M. Alzahrani, Mohamed K. Awad, Siham A. Al-Issa, Ghaferah H. Al-Hazmi, Mohamed S. Nafie
Формат: Artigo
Мова:Inglês
Опубліковано: Taylor & Francis Group 2023-12-01
Серія:Journal of Enzyme Inhibition and Medicinal Chemistry
Предмети:
Онлайн доступ:https://www.tandfonline.com/doi/10.1080/14756366.2022.2163996
Теги: Додати тег
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