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hnRNPK promotes gastric tumorigenesis through regulating CD44E alternative splicing

Abstract Background The high prevalence of alternative splicing among genes implies the importance of genomic complexity in regulating normal physiological processes and diseases such as gastric cancer (GC). The standard form of stem cell marker CD44 (CD44S) and its alternatives with additional exon...

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Principais autores: Wei-zhao Peng, Ji-xi Liu, Chao-feng Li, Ren Ma, Jian-zheng Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-12-01
coleção:Cancer Cell International
Assuntos:
hnRNPK
Gastric cancer
SRSF1
CD44E
Alternative splicing
Acesso em linha:https://doi.org/10.1186/s12935-019-1020-x
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