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Upadacitinib monotherapy versus methotrexate monotherapy in patients with rheumatoid arthritis: efficacy and safety through 5 years in the SELECT-EARLY randomized controlled trial

Abstract Background To evaluate the efficacy and safety of upadacitinib monotherapy versus methotrexate (MTX) monotherapy over 5 years among MTX-naïve patients with moderately to severely active rheumatoid arthritis (RA) in the long-term extension (LTE) of the phase 3 SELECT-EARLY trial. Methods Pat...

Deskribapen osoa

Gorde:
Egile Nagusiak: Ronald van Vollenhoven, Vibeke Strand, Tsutomu Takeuchi, Nilmo Chávez, Pablo Mannucci Walter, Atul Singhal, Jerzy Swierkot, Nasser Khan, Xianwei Bu, Yihan Li, Sara K. Penn, Heidi S. Camp, Jacob Aelion
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2024-07-01
Saila:Arthritis Research & Therapy
Gaiak:
JAK inhibitor
Methotrexate
Targeted synthetic DMARD
Upadacitinib
Rheumatoid arthritis
Randomized controlled trial
Sarrera elektronikoa:https://doi.org/10.1186/s13075-024-03358-x
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