Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

Elements of the hypoxia inducible factor (HIF) transcriptional system, a key regulator of the cellular hypoxic response, are up-regulated in a range of cancer cells. HIF is fundamentally involved in tumor angiogenesis, invasion, and energy metabolism. Inhibition of the transcriptional activity of HI...

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書誌詳細

主要な著者:	Emily M. Harris, Jonathan D. Strope, Shaunna L. Beedie, Phoebe A. Huang, Andrew K. L. Goey, Kristina M. Cook, Christopher J. Schofield, Cindy H. Chau, Melissa M. Cadelis, Brent R. Copp, Kirk R. Gustafson, William D. Figg
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2018-07-01
シリーズ:	Marine Drugs
主題:	discorhabdins hypoxia HIF angiogenesis marine natural products alkaloids
オンライン･アクセス:	http://www.mdpi.com/1660-3397/16/7/241
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