Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

The telomeric CTC1/STN1/TEN1 (CST) complex has been implicated in promoting replication recovery under replication stress at genomic regions, yet its precise role is unclear. Here, we report that STN1 is enriched at GC-rich repetitive sequences genome-wide in response to hydroxyurea (HU)-induced rep...

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主要な著者:	Megan Chastain, Qing Zhou, Olga Shiva, Leanne Whitmore, Pingping Jia, Xueyu Dai, Chenhui Huang, Maria Fadri-Moskwik, Ping Ye, Weihang Chai
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2016-08-01
シリーズ:	Cell Reports
主題:	CTC1/STN1/TEN1 replication stress RAD51 genome stability
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124716308464
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